neuronavigation: principles, clinical applications and potential pitfalls.

Neuronavigation: Principles, Clinical Applications and Potential Pitfalls

Localization of brain lesions and prevention of damage to vital structures are important in operation of brain pathologies. Despite development of many techniques including angiography, MRI, sonography, and frame base stereotaxy, a more accurate localizing technique is still needed (1, 2). A step forward to achieve this goal is to develop a navigation system. In this manuscript, we explained so...

Principles of Neuronavigation

Background and Aim: Numerous efforts over the past century have been performed. Various innovation techniques are increasingly gaining attention and gradually established the foundation of recent significant developments in the world of neurosurgery, among which varied stereotactic neuro-navigation designs and other novel emerging systems are being quotidian developed. This narrative review ai...

Neuronavigation. Principles. Surgical technique.

Neuronavigation and stereotaxy are techniques designed to help neurosurgeons precisely localize different intracerebral pathological processes by using a set of preoperative images (CT, MRI, fMRI, PET, SPECT etc.). The development of computer assisted surgery was possible only after a significant technological progress, especially in the area of informatics and imagistics. The main indications ...

Proteomics of breast cancer: principles and potential clinical applications.

Progresses in screening, early diagnosis, prediction of aggressiveness and of therapeutic response or toxicity, and identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the mo...

Potential pitfalls of clinical prediction rules.

Small interfering RNA; principles, applications and challenges--

Gene silencing using RNAi (RNA interference), has recently been used as a successful laboratory technique in determining the function and control of gene expression and provides a wide range of applications in molecular biology and gene therapy. RNAi is a method of suppressing gene expression. In this direction, a single-stranded RNA molecule of about 21–23 nucleotides, called siRNA (small inte...